Tag archives for GDH

Glutamate dehydrogenase: A study of its physico-chemical properties from the liver of mice of two different age groups


Glutamate dehydrogenase (GDH) an enzyme which catalyze the reversible formation of glutamate from \alpha-ketoglutarate, occupies a central position in mammalian nitrogen metabolism since the reaction which it catalyze provides the major pathway by which ammonia become bound to the \alpha-carbon atom of an \alpha-ketoacid to generate glutamate. The activity of GDH is influenced by a number of physical and chemical parameters that contributes to its stability as well as its activity. Physico-chemical studies of partially purified GDH from two age groups (10- and 90-day old), from the mice liver tissue are reported.

Keywords GDH, physico-chemical, mice